Unlike traditional injections that just temporarily suppress inflammation or lubricate the joint, Arthrosamid is an injectable polyacrylamide hydrogel (iPAAG). It consists of 97.5% water and 2.5% cross-linked polyacrylamide. When injected, it permanently integrates into the tissue lining the inner capsule of your knee, providing a durable, cushion-like barrier.

1. Long-Lasting Pain Relief

The most significant benefit of Arthrosamid is its durability. While traditional injections often wear off within a few months, clinical studies show that a single Arthrosamid injection can provide sustained pain relief for three to five years.

2. A Single-Dose Procedure

You won’t need to return for a series of ongoing shots. Arthrosamid is administered as a one-time, 6 ml injection directly into the knee joint.  It is a highly efficient way to manage chronic arthritic pain without constantly visiting a clinic.

3. Helps Delay or Avoid Surgery

For many patients, a total or partial knee replacement is a daunting prospect. Arthrosamid bridges the gap between conservative treatments (like weight loss and physiotherapy) and invasive surgery.  By significantly improving pain and function, it can help you delay joint replacement surgery for years—or help you avoid it entirely if you are not a surgical candidate.

4. Minimally Invasive with Fast Recovery

Because Arthrosamid is an outpatient procedure performed under local anaesthetic, there are no hospital stays or lengthy rehabilitation periods.  The injection takes about 10 to 15 minutes.  You can walk out of the clinic the same day and usually return to your normal, non-strenuous activities within just a few days.

5. Outperforms Traditional Injections

Steroid injections provide quick but short-lived anti-inflammatory relief, and there are concerns that prolonged use may actually damage cartilage.Hyaluronic acid (HA) acts as a temporary lubricant that is quickly broken down by the body. Arthrosamid offers superior, longer-lasting symptom control compared to both of these conventional options.

6. Restores Cushioning and Lubrication

Arthrosamid works physically rather than chemically. It physically thickens your synovial fluid and mechanically softens the surrounding joint tissue.  By “cooling the inflammatory” effect inside your knee, it drastically reduces the symptoms that makes osteoarthritis so painful.

7. It Doesn’t Break Down in the Body

The reason Arthrosamid lasts so long is that it is a non-biodegradable hydrogel.  Your body does not metabolize or absorb it.  Once it integrates into your synovial tissue, the hydrogel network stays exactly where it needs to be, providing continuous protection year after year.

8. Restores Mobility and Reduces Stiffness

Pain is only half the battle with osteoarthritis; the other half is stiffness. Patients who receive Arthrosamid consistently report significant improvements in knee function and a reduction in morning stiffness, making it easier to walk, climb stairs, and return to the active hobbies they love.

9. Excellent Safety Profile

The polyacrylamide hydrogel used in Arthrosamid has been safely used in various medical procedures for over 20 years.Clinical trials for knee osteoarthritis show it has a low risk of side effects.  You might experience mild, temporary swelling or discomfort at the injection site, but systemic complications are incredibly rare.

10. Broad Suitability

Arthrosamid is an excellent option for a wide variety of patients:

  • Younger, active individuals who want to delay joint replacement.

  • Older patients who may have medical conditions that make surgery too risky.

  • People whose jobs require frequent kneeling or mobility, making a knee replacement impractical.

While no injection can reverse arthritis completely, Arthrosamid represents a massive leap forward in managing the condition. By offering years of symptom relief from a single, quick procedure, it allows patients to reclaim their mobility and their quality of life.

If you are struggling with knee pain, consult with Prof Divya Prakash to find out if Arthrosamid is the right next step for your joint health.